Friday, December 18, 2009

What is a peptic ulcer?

What is a peptic ulcer
Peptic ulcer is open injury or inflammation of the protective layer and the lining of the stomach, duodenum or esophagus. Ulcer occurs under the influence of hydrogen chloride of stomach acid and enzymes of pepsin, when there is damage to the protective layer on the intestinal mucosa of these organs.

About 10% of people had a peptic ulcer at least once during their lives, and 2-3% of people get it every year. The disease affects people of all ages, but is significantly less common in younger people. Duodenal ulcers usually first appears between the ages of 30 to 50 years, and is more common in men than in women, whereas gastric ulcer is most common in the age above 60, and is more common in women than in men.

Today it is known that about 80% of gastric ulcers and about 90% of duodenal ulcer is a consequence of inflammation and damage of the protective layer of mucous that bacterium Helicobacter pylori causes. This bacterium is free in the stomach due to its resistance to stomach acid because of secretion of specific enzymes.

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